| Diaphragmatic function in malignant hyperthermia |
|
Worldwide (International, UK and EU) |
None |
| Epigenetic therapy using ultrasound-triggered microbubble drug delivery for colorectal cancer |
|
Worldwide (International, UK and EU) |
None |
| Metabolic regulation of anti-tumour T cell immunity |
|
Worldwide (International, UK and EU) |
None |
| 11β-hydroxysteroid dehydrogenase type 1: a novel target to improve wound healing in diabetes |
|
Worldwide (International, UK and EU) |
None |
| Characterisation of a pre-osteoblast subset of human mesenchymal stem cells: implications for novel osteoarthritis and osteoporosis treatment development |
|
Worldwide (International, UK and EU) |
None |
| Combination oncolytic virotherapy for the treatment of Haematological malignancies |
|
Worldwide (International, UK and EU) |
None |
| Computational approaches to understanding the mechanosensitive Piezo1 channel activation mechanism |
|
Worldwide (International, UK and EU) |
None |
| Developing pluripotent stem cell models of inherited retinal diseases |
|
Worldwide (International, UK and EU) |
none |
| Development of a T-cell subset phenotyping, ready-to-use, flow cytometry kit for patients with rheumatoid arthritis |
|
Worldwide (International, UK and EU) |
None |
| Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA) |
|
Worldwide (International, UK and EU) |
None |
| Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment |
|
Worldwide (International, UK and EU) |
None |
| Exploring the mitotic functions of ASPM in human brain size regulation |
|
Worldwide (International, UK and EU) |
none |
| Gastroesophageal reflux in respiratory disease: pathogenic role and improved management |
|
Worldwide (International, UK and EU) |
None |
| Genetic studies of corneal endothelial dystrophies and development of alternative treatment options |
|
Worldwide (International, UK and EU) |
None |
| Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness |
|
Worldwide (International, UK and EU) |
None |
| How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta |
|
International (excluding EU) |
None |
| Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer |
|
Worldwide (International, UK and EU) |
None |
| Improving surgical outcomes for colorectal cancer patients by pre-operative intervention. |
|
Worldwide (International, UK and EU) |
None |
| Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death |
|
Worldwide (International, UK and EU) |
None |
| Novel regulators of +TIP localisation and function |
|
Worldwide (International, UK and EU) |
None |
| Oncogenic reprogramming of the immune system |
|
Worldwide (International, UK and EU) |
None |
| Oncolytic virus immunotherapy to sensitise liver cancers to immune checkpoint blockade |
|
Worldwide (International, UK and EU) |
None |
| Partial human genome RNAi screen to identify genes involved in brain size regulation and cancer development. |
|
Worldwide (International, UK and EU) |
None |
| Pre-clinical testing of new therapeutic treatments for cystic kidney disease |
|
International (excluding EU) |
None |
| Pre-receptor regulation of glucocorticoid target genes in human skin |
|
Worldwide (International, UK and EU) |
None |
| Primary Immunodeficiencies: molecular genetics and the underlying biological mechanisms of disease |
|
Worldwide (International, UK and EU) |
None |
| Starving cancer cells to death |
|
Worldwide (International, UK and EU) |
None |
| Sun exposure as a novel risk factor for Zika virus infection |
|
Worldwide (International, UK and EU) |
None |
| Switching off immunity in health and disease |
|
Worldwide (International, UK and EU) |
None |
| The functional characterization of the tumour suppressor gene CSMD1 in breast cancer |
|
Worldwide (International, UK and EU) |
none |
| The genetic basis of cognitive impairment in intellectual disability and schizophrenia |
|
Worldwide (International, UK and EU) |
None |
| Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye |
|
Worldwide (International, UK and EU) |
None |
| Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease. |
|
Worldwide (International, UK and EU) |
None |
