Medicine MRes Research Projects

What’s available at Leeds?

Medical research plays an enormous role in improving patient care and outcomes. Through our course, you’ll develop your specialist skills and knowledge while also gaining the experience to feel equipped for a career in the field.

At Leeds, our MRes Medicine is an exciting and challenging course designed for those who want to advance their research skills and be immersed in a research project. 

Your nine-month project will help you to develop specialised knowledge, as well as design and undertake a substantial piece of publishable research. While studying with us, you’ll be based in one of our internationally-renowned institutes and be supervised by leading experts in their field. To help you specialise based on your interests, you can choose from a range of research opportunities from applied health, cancer and pathology, cardiovascular, genes and development, medical education and musculoskeletal topics. What’s more, it can be possible for our students to self-design a project if there is a University of Leeds researcher that they are particularly keen to collaborate with while at Leeds.

Here’s a view of the projects currently available at Leeds. Please note that this page will continue to be updated while more projects become available.

Dr Katie Simmons  

The development of modulators of IR-IGF1R hybrids as a potential treatment for Type 2 Diabetes  


Dr Lee Roberts  

The impact of type 2 diabetes on cardiac metabolic phenotype in patients with severe aortic stenosis   

Dr Rebecca Spencer  

Assessing inter- and intra-rater reliability of a novel adverse event grading system for clinical trials in pregnancy  


Extracellular vesicles (EVs) as biomarkers of outcome in pregnancies complicated by early-onset fetal growth restriction (FGR)  

Predicting outcome in pregnancies where the fetus is small-for-gestational age  

Investigating the role of proteins associated with the development of abnormal umbilical artery Dopplers in early-onset fetal growth restriction on placental development and function  

Professor Daniel Peckham  

Are CFTR modulator therapies effective at reducing inflammation in patients with rare CFTR mutations?  


Dr Salvatore Papa  

The regulation of metabolism on drug response in cancer  


Dr Niamh Forde  

Understanding the role of non-coding RNAs in implantation failure  


Understanding the contribution of obesity associated metabolic stressors to implantation failure in humans  

Optimising 3D approaches to generate in vitro models to understand pregnancy loss  

Dr S Saha  

Diagnostic and Prognostic markers of stroke outcomes  


Zhan Ong  

Development of novel membrane active peptide therapeutics to combat antimicrobial resistance  

EC Stoner (Molecular and Nanoscale Physics)  

Dr Ana Tiganescu  

Investigating the interplay between 11β-HSD1, hypoxia and wound healing in db/db mice  


Regulation of the human skin microbiome by  11β-HSD1  

Hull York Medical School  

Dr James Poulter  

Dissecting the role of the mTOR signalling pathway in polycystic kidney organoid models  


Dr Manoj Sivan    


Home-based pain management using Brain Neuromodulation Intervention Technology (BNIT)  


Understanding the connection between Long COVID and Chronic Fatigue Syndrome  

Dr Christine Diggle  

Investigation into the control of SLCO2A1 expression in colon cancer  



Dr Milene Volpato  

CpG island methylation regulates the expression of genes involved in colorectal cancer cell response to EPA  

Dr Laura Matthews  

Investigating the effects of anti-inflammatory steroids on existing and emerging treatments for aggressive brain cancer  

Dr Thomas Pike  

Association between pancreatitis and inflammatory bowel disease  

Dr Georgia Mavria  

Molecular mechanisms blood vessel abnormality in brain tumours and their contribution to therapeutic resistance.  

Dr Manir Ali  

Genetic analysis of the non-inflammatory eye condition, keratoconus, in families using next-generation sequencing  

Dr Liz Valleley  

Targeted delivery of vitamin C and decitabine for KRAS/BRAF-mutated colorectal cancer treatment.  

Mr Stephen Chapman   

Improving pain management after surgery: National mixed method study