Clinical trials

Clinical trials provide the gold standard method to supply the evidence base for Health Service interventions in the NHS. At any one time the University of Leeds sponsors about 45 academic-designed and led clinical trials, ranging from phase I to phase IV. These are across a spectrum of diseases and treatment types and utilise the wide range of multidisciplinary methodological and chief investigator expertise across the Institutes of the School of Medicine.

Our UK Clinical Research Collaboration (UKCRC) fully registered specialist clinical trials unit, Leeds Clinical Trials Research Unit (CTRU) is based in the Leeds Institute of Clinical Trials Research and conducts national and international randomised and early phase clinical trials in a variety of clinical fields. It incorporates the following research groups:

• Complex Interventions
• Early Phase Cancer
• Late Phase Cancer
• Leeds Cancer Research UK Clinical Trials Centre
• Myeloma UK Concept and Access Research Programme (CARP)
• Surgical Interventions, Diagnostics and Devices
• Yorkshire Cancer Research Early Phase Clinical Trials Centre

The University and the Leeds Teaching Hospitals NHS Trust have a joint quality assurance office which provides regulatory guidance and support for investigators, in both organisations, for Medicines and Healthcare products Regulatory Agency (MHRA) regulated drug studies.

Further guidance is available from the Leeds Teaching Hospitals NHS Trust.