Master of Research in Medicine - Projects
The list of available research projects for 2019/20 is now available. We strongly encourage applicants to contact the supervisory team to discuss a project before applying to the programme. In the personal statement section of your application, let us know of your three preferred projects.
|
Title |
Supervisors |
Institute |
|
Investigation of tyrosine-kinase proteins TTK, VRK1 and BRD4 as prognostic biomarkers in ovarian cancer |
Dr Nic Orsi n.m.orsi@leeds.ac.uk nicolas.orsi@nhs.net Dr Sandra Bell |
LIMR |
|
Apoptosis-resistance in cancer cells |
Dr Salvatore Papa |
LIMR |
|
Teicoplanin anaphylaxis: Development of a diagnostic pathway, and elucidation of the underlying allergic mechanism. |
Professor P M Hopkins Dr Louise Savic louise.savic@nhs.net Dr Sinisa Savic s.savic@leeds.ac.uk |
LIMR |
|
Combined oncolytic virus and checkpoint modulation for the treatment of liver cancer |
Dr Adel Samson Dr Emma West |
LIMR |
|
Identifying modulators of steroid receptor signalling in breast cancer |
Laura Matthews James Thorne |
LIMR |
|
The role of steroid receptors in modulating cholesterol metabolite signalling in breast cancer |
James Thorne Laura Matthews |
LIMR |
|
Investigating whether schizophrenia is caused by a trinucleotide repeat expansion. |
Dr Manir Ali |
LIMR |
|
Clinical trial investigating transcutaneous vagus nerve stimulation as a novel treatment for constipation |
Mr Stephen Chapman Prof David Jayne |
LIMR/LTHT |
|
Pilot study to investigate the potential mechanisms of action for Plasma Exchange in patients with Acute Liver Failure |
Prof Roz Banks Dr Joanna Moore Dr Marina Karakantza Prof Mark Bellamy Dr Niki Snook |
LIMR/LTHT |
|
Remote sensing for preoperative assessment |
Dr Hafdis Svavarsdottir Prof David Jayne |
LIMR/LTHT |
|
Understanding the role of prognostic tools in routine practise – A qualitative study with clinicians |
Katie Spencer Galina Velikova |
LIMR/LTHT |
|
Exercise and nutrition in patients with colorectal disease undergoing surgery |
Dermot Burke d.burke@leeds.ac.uk |
LIMR/LTHT |
|
Collection and biochemical characterisation of wound exudates from diabetic patients |
Dr Giuseppe Tronci Mr. David Russell
|
Dept. Oral Biology (School of Dentistry)/LIMR/LTHT |
|
Exploring the impact of fetal sex on placental function in pregnancies complicated by maternal diabetes |
Dr Karen Forbes Dr Kate Timms |
LICAMM |
|
Examining the impact of dietary derived extracellular vesicles on human placental vascular development and function |
Dr Karen Forbes k.a.forbes@leeds.ac.uk |
LICAMM |
|
Examining the interaction between maternal glucose, placental miRNAs and fetal growth in pregnancies complicated by maternal diabetes |
Dr Karen Forbes Professor Eleanor Scott |
LICAMM |
|
Tracking the fate of vascular smooth muscle cells in a surgical model of abdominal aortic aneurysms (AAA) using the Confetti (Brainbow) multi-fluorescent transgenic mouse line |
Lucinda Craggs Dr Marc Bailey |
LICAMM |
|
Effect of β2 Glycoprotein I on Blood Coagulation and Lysis |
Helen Philippou Emma Hethershaw Brian Jackson |
LICAMM/Astbury Protein Production Facility |
|
Do Steroids Prevent the Development of Oesophageal Cancer? Identifying the role of glucocorticoids in preventing the progression of Barrett’s oesophagus to oesophageal adenocarcinoma |
Dr Ana Tiganescu, Dr Chris Jones |
LICAMM |
|
Phospho-proteomic analysis of platelet signalling cascades by flow cytometry: from mechanism to translational medicine at the single-cell level. |
Khalid Naseem Ramzi Ajjan |
LICAMM |
|
Decreasing muscular ectopic lipid stores to prevent Type 2 Diabetes |
Dr Lee Roberts Klaus Witte |
LICAMM |
|
Identification and Evaluation of Small-molecule Modulators of Protein-Protein Interactions involved in Cardiovascular Disease and Type 2 Diabetes. |
Dr Katie Simmons Prof M T Kearney |
LICAMM |
|
Home-based Brainwave Entrainment Technology (hBET) for management of chronic pain and sleep disturbance. A feasibility study |
Dr Manoj Sivan Prof Rory O’Connor |
LTHT |
|
Personalised approach to restoration of arm function in people with high-level tetraplegia |
Prof Rory O’Connor R.J.O'Connor@leeds.ac.uk Dr Manoj Sivan
|
LTHT/LIRMM |
|
Optimising the management of post-surgical intra-abdominal infection |
Dermot Burke Dr Andrew Kirby, Dr Shadia Ahmed |
LTHT |
|
Oran antimicrobial therapy for pyelonephritis-a review of the literature and a pharmacokinetic-pharmacodynamic analysis. |
Andrew Kirby Jonathan Cattrall |
LTHT |
|
Understanding gastrointestinal motility function and dysfunction in children. |
Mr Jonathan Sutcliffe Professor Jim Deuchars |
FBS/LTHT |
|
Are there significant sex differences in the muscle abnormalities displayed by patients with heart failure? |
Scott Bowen Klaus Witte |
FBS |
|
An Introduction to Big Data and Data Science – The Impact of Genetic Phenotype on Outcomes in Ovarian and Breast Cancer. |
Prof Geoff Hall Dr Kieran Zucker Dr Sue Cheeseman |
LIDA |
|
Improving Triple Negative Breast Cancer survival by dietary targeting of LDL-cholesterol in host-cells of the tumour microenvironment |
Dr James L. Thorne Dr Giorgia Cioccoloni |
School of Food Science and Nutrition (MAPS) |
|
What changes do patients make to their diet in response to receiving a cancer diagnosis? |
Hannah Ensaff James Thorne |
School of Food Science and Nutrition (MAPS) |
|
Development of novel nanoparticle-peptide therapeutics for antimicrobial applications |
Dr Zhan Ong |
School of Physics and Astronomy (MAPS) |
LIMR: Leeds Institute of Medical Research at St James’s; LICAMM: Leeds Institute of Cardiovascular and Metabolic Medicine; LIRMM: Leeds Institute of Rheumatic and Musculoskeletal Medicine; FBS: Faculty of Biological Sciences; LTHT: Leeds Teaching Hospital Trust; MAPS: Faculty of Mathematics and Physical Sciences; LIDA: Leeds Institute of Data Analytics