Dr Manir Ali
- Position: Senior Research Fellow
- Areas of expertise: vision research; genetics; family studies; ophthalmology; neuroscience; molecular biology; next generation sequencing
- Email: M.Ali@leeds.ac.uk
- Phone: +44(0)113 343 8420
- Location: 8.14 Wellcome Trust Brenner Building
I read Biological Sciences specialising in Molecular Biology at the University of Edinburgh, graduating with a BSc honours degree in 1990. I then moved to Cambridge as a postgraduate research assistant in the Department of Medicine at Addenbrooke’s Hospital with Professor Tim Cox, where I studied for a PhD at the University of Cambridge on the molecular biology of hereditary fructose intolerance.
I moved to the St. James’s University Hospital campus in Leeds in 1996 to work with Professor John Isaacs as a post-doc researching gene expression in anergic T-cells and synovial biopsies from rheumatoid arthritis patients. This work involved spending time at GlaxoSmithKline in Stevenage and I was awarded the British Society of Rheumatology Young Investigator award in 2000. Back in Leeds, in 2002, I worked with Professor Yanick Crow as a research fellow on the molecular genetics of the neurodevelopmental condition, Aicardi-Goutieres syndrome, and in 2004, I worked with Professor Chris Inglehearn in collaboration with the Roslin Institute, on the genetics of blind chickens.
I became an independent academic fellow following a New Investigator Award from the Medical Research Council in 2006 and was tenured in 2009 as a Senior Research Fellow and Group Leader in the Section of Ophthalmology & Neuroscience.
- Group Leader
My research aims to find the genetic cause and molecular basis of inherited eye disease to aid diagnosis and search for better treatments for these conditions. I am a member of the Leeds Vision Research Group, the Leeds Psychosis Research Group, the UK Inherited Retinal Disease Consortium and the European Retinal Disease Consortium.
- PhD, University of Cambridge
- BSc Honours, University of Edinburgh
- UK Eye Genetics Group (EGG)
- Association for Research in Vision and Ophthalmology (ARVO)
I teach on the MBChB programme, the MSc in Molecular Medicine and am a personal tutor to undergraduate medical students in years 1 and 2.
Research groups and institutes
- Leeds Institute of Medical Research at St James's
- Genetics and genomics
<li><a href="//phd.leeds.ac.uk/project/56-genetic-studies-of-corneal-endothelial-dystrophies-and-development-of-alternative-treatment-options">Genetic studies of corneal endothelial dystrophies and development of alternative treatment options</a></li>
<li><a href="//phd.leeds.ac.uk/project/210-investigating-the-molecular-basis-of-optic-nerve-degeneration-in-glaucoma-to-try-and-develop-a-personalized-medicine-strategy-for-treatment">Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment</a></li>