Nuria Navarro Coy

Profile

I worked for seven years at the Clinical Trials Research Unit (CTRU) at the University of Leeds, which is one of the largest and most established CTU’s in the UK with a portfolio of over 80 trials. I was a Senior Trial Manager (STM) with oversight of four large multi-centre trials and one single-centre trial. This included being the operational lead for the newly established Musculoskeletal Portfolio with responsibility for several trials including large multi-centre ones. I have collaborated in the design of trials and applying for funding and have a wealth of experience in the delivery of trials from protocol writing, ethics and governance arrangements and data collection through to publication of the trial results. Prior to my role in clinical trials I gained laboratory experience during my undergraduate Genetics degree, my intercalated academic year in the United States (U.S.) and my research technician position at St. James’s University Hospital (SJUH) within Professor Robert Mueller’s research group.

I completed an MPhil on recessive hereditary deafness in children. The results of the MPhil research indicated that the identification of recessive mutations in isolated populations of different ethnic origins should not be extrapolated to European/UK populations due to ethnic variation. I also collaborated in a project involving the analysis of mutations in mitochondrial DNA leading to recessive deafness and their distribution in the different haplogroups in the Caucasian population. My laboratory experience started my interest in genetic and environmental differences amongst populations and the application of my knowledge and skills towards research that was more patient applicable.

This directed me to undertake an MRes in Bioinformatics with the aim of becoming proficient in the use of electronic resources, computer programming and database development. My educational and career paths have led me to my current position at the Leeds Institute of Rheumatic and Musculoskeletal Medicine where I am working in the field of rheumatoid arthritis, specifically focusing on using registry data to inform and complement RCT data and lead to more clinically relevant efficacy evaluation and thereby ensure improved patient benefits. My current post involves the delivery of one of the components of a European project (IMI BeTheCure) aiming to provide an alignment of several different in vivo models of arthritis with different subsets of human arthritis, in such a way that therapy and prevention developed in these models, can be further developed, tested and ultimately used in subsets of human arthritis. The remit of this project specifically focuses on the application in human arthritis, developing measures to deliver efficient and accurate patient recruitment strategies for clinical trials that include patients along what is termed the rheumatoid arthritis (RA) disease continuum. I am responsible for designing the methods, evaluating the results and coordinating the development of new recruitment criteria for clinical trials in RA. I am also expected to manage the project in accordance with the milestone and resources outlined in the grant application.

Research groups and institutes

  • Leeds Institute of Rheumatic and Musculoskeletal Medicine