Sam
- Position: Postdoc Researcher
- Areas of expertise: MRI, NMR, Neuroimaging, pre-clinical imaging, cardiac imaging
- Email: S.Paterson@leeds.ac.uk
Profile
BSC Physics – University of Aberdeen
PhD in medical physics (MRI) – University of Glasgow
Research groups and institutes
- Leeds Institute of Cardiovascular and Metabolic Medicine
Opportunities
- Diaphragmatic function in malignant hyperthermia
- Epigenetic therapy using ultrasound-triggered microbubble drug delivery for colorectal cancer
- Metabolic regulation of anti-tumour T cell immunity
- 11β-hydroxysteroid dehydrogenase type 1: a novel target to improve wound healing in diabetes
- Atomic force microscopy studies of the molecular mechanisms of nested genes related to tooth formation
- Characterisation of a pre-osteoblast subset of human mesenchymal stem cells: implications for novel osteoarthritis and osteoporosis treatment development
- Combination oncolytic virotherapy for the treatment of Haematological malignancies
- Computational approaches to understanding the mechanosensitive Piezo1 channel activation mechanism
- Developing pluripotent stem cell models of inherited retinal diseases
- Development of a T-cell subset phenotyping, ready-to-use, flow cytometry kit for patients with rheumatoid arthritis
- Digital manufacturing of complete dentures
- Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
- Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
- Exploring the mitotic functions of ASPM in human brain size regulation
- Gastroesophageal reflux in respiratory disease: pathogenic role and improved management
- Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
- Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
- How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
- Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
- IGF axis regulation of matrix mineralisation of dental stem cell populations
- Immunological complicity in evolution of potentially malignant oral lesions
- Improving surgical outcomes for colorectal cancer patients by pre-operative intervention.
- Investigating the genetic association between systemic disease and oral health through genome-wide association study
- Investigation of matrix-mineral interactions of enamel formation in Amelogenesis Imperfecta
- Metabolic labelling approach for the incorporation of functional groups in therapeutic DNA enabling advanced payload delivery strategies in peptide-based gene delivery
- Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
- Novel regulators of +TIP localisation and function
- Oncogenic reprogramming of the immune system
- Oncolytic virus immunotherapy to sensitise liver cancers to immune checkpoint blockade
- Oral health and cognitive function in old age
- Osteochondral tissue engineering using novel epigenetic approaches and multi-layered cell sheet technology
- Partial human genome RNAi screen to identify genes involved in brain size regulation and cancer development.
- Peptide-based matrix gene delivery for tissue regeneration and anti-microbial therapy targeting periodontal disease
- Pre-clinical testing of new therapeutic treatments for cystic kidney disease
- Pre-receptor regulation of glucocorticoid target genes in human skin
- Primary Immunodeficiencies: molecular genetics and the underlying biological mechanisms of disease
- Starving cancer cells to death
- Sun exposure as a novel risk factor for Zika virus infection
- Switching off immunity in health and disease
- The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
- The genetic basis of cognitive impairment in intellectual disability and schizophrenia
- The potential use of bioactive peptides from food and waste as anti-cariogenic agents
- Transient arrest of cell ageing during amplification of human cells in culture
- Understanding the causes of developmental tooth defects using a high-throughput genomic screening approach
- Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
- Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease.