Dr Carolyn Hurst

Dr Carolyn Hurst


I am a senior postdoctoral research fellow working with Professor Maggie Knowles in the Leeds Institute of Medical Research. My research interests include genomic and transcriptomic profiling and exome sequencing of bladder tumours.

I received my PhD in population genetics from Swansea University in 1993. After finishing my PhD I moved to the Memorial University of Newfoundland in Canada where I worked as a postdoctoral researcher in the field of salmonid genomics and molecular evolution. I returned to the UK in 1994 to take up a postdoctoral position researching into molecular diagnostics at the University of Greenwich. In 2001 I moved to the Cancer Research UK Clinical Centre at St James’s University Hospital (Leeds) to work as a CRUK funded Senior Scientific Officer in Prof. Maggie Knowles’s group researching into the molecular features of bladder cancer. Since 2004 I have continued my research in Prof. Knowles’s group as a Yorkshire Cancer Research funded University of Leeds postdoctoral fellow in the Section of Molecular Oncology.

Research interests

I am interested in all aspects of the molecular genetics of bladder cancer with a particular focus on genomics and genome-wide profiling using transcriptome, miRNA, methylation, and copy number analysis. My current research is aimed at defining molecular subgroups of bladder tumours using integrated genomic approaches, and identifying ‘novel’ molecular drivers of bladder cancer by whole-exome sequencing.


  • PhD Population genetics
  • MSc Shellfish Biology, Fisheries and Culture
  • BSc (Hons) Biological Sciences

Research groups and institutes

  • Leeds Institute of Medical Research at St James's
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