Dr Rui-Gang Xu
- Position: Research Fellow
- Email: R.Xu1@leeds.ac.uk
- Website: Googlescholar | Researchgate | ORCID
Profile
Rui-Gang Xu obtained a BSc in Pharmaceutical Sciences from Shandong University of Traditional Chinese Medicine in 2010. In 2013, he completed his postgraduate training with an MMed in Medicinal Chemistry with Professor Feng-Wu Liu at Zhengzhou University. He obtained his Ph.D. in Structural Biology with Professor Fred Antson at the University of York in 2017. After graduation, Rui-Gang joined Professor Robert Ariëns’ research team at the University of Leeds.
Research interests
My research is focused on investigating molecular and structural mechanisms of GPVI-fibrinogen interaction. Several biophysical techniques are used to explore how they interact, including surface plasma resonance (SPR) and microscale thermophoresis (MST). To obtain structural information, Cryo-electron microscopy and X-ray crystallography are utilised to resolve the structural basis of the complex. The revealed mechanisms can be used in the future to design potential anti-thrombotic drugs.
Qualifications
- BSc in Pharmaceutical Sciences
- MMed in Medicinal Chemistry
- PhD in Structural Biology
Research groups and institutes
- Leeds Institute of Cardiovascular and Metabolic Medicine