Dr Rui-Gang Xu

Dr Rui-Gang Xu


Rui-Gang Xu obtained a BSc in Pharmaceutical Sciences from Shandong University of Traditional Chinese Medicine in 2010. In 2013, he completed his postgraduate training with an MMed in Medicinal Chemistry with Professor Feng-Wu Liu at Zhengzhou University. He obtained his Ph.D. in Structural Biology with Professor Fred Antson at the University of York in 2017. After graduation, Rui-Gang joined Professor Robert Ariëns’ research team at the University of Leeds.

Research interests

My research is focused on investigating molecular and structural mechanisms of GPVI-fibrinogen interaction. Several biophysical techniques are used to explore how they interact, including surface plasma resonance (SPR) and microscale thermophoresis (MST). To obtain structural information, Cryo-electron microscopy and X-ray crystallography are utilised to resolve the structural basis of the complex. The revealed mechanisms can be used in the future to design potential anti-thrombotic drugs.


  • BSc in Pharmaceutical Sciences
  • MMed in Medicinal Chemistry
  • PhD in Structural Biology

Research groups and institutes

  • Leeds Institute of Cardiovascular and Metabolic Medicine