Dr Christine Diggle


I have a BSc in Biological Sciences from the University of Birmingham, and a PhD in Human Genetics from Newcastle University. I have been based in the Section of Genetics since 2004.


  • MSc Module leader

Research interests

My focus is to identify the genetic basis of disease, and investigate the biochemical, cellular and physiological effects. Of particular interest is the investigation of rare inherited disease, this involves the identification of mutations and variants in DNA samples and using in-house bespoke bioinformatic software. Understanding how these genes and genetic changes cause disease requires further functional studies, such as cellular and biochemical in vitro experimental approaches, and the use of animal models. It can involve the development of assays for research and diagnostic purposes.

By research on rare diseases my aim is also to also to understand how these genes have a role in more complex diseases, and the mechanisms involved in these processes. This research will allow us to identify possible targets for therapeutic intervention.


  • BSc
  • PhD

Professional memberships

  • Biochemical Society
  • Associate Fellow of the Higher Education Academy (AFHEA).

Student education

I have a role in both Undergraduate and Postgraduate student teaching, through delivering tutorials,  lectures, and also assessing coursework.

Research groups and institutes

  • Leeds Institute of Medical Research at St James's
  • Rare Diseases & Genetics
<h4>Postgraduate research opportunities</h4> <p>We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. Our <a href="https://phd.leeds.ac.uk">research opportunities</a> allow you to search for projects and scholarships.</p>