Dr Melissa Maguire


I joined Leeds Teaching Hospitals (LTHT) in 2011 as Consultant Neurologist and since 2017 hold the Honorary title of Associate Professor within the Leeds Institute of Medical Research.

I am research lead for Neurology at LTHT and have an established track record for delivering phase II to phase IV commerical and non-commerical clinical trials of portfolio studies investigating anti-epileptic drugs. I was also the NIHR Division 4 lead for Neurological disorders in Yorkshire and Humber between 2016-2020 and demonstrated a consistent high national ranking for recruitment and study engagement within the geographical patch.

My medical doctorate from the University of Liverpool researched into selection biases in non-randomised and randomised studies of anti-epileptic drugs. The MD was awarded the prestigious Gower’s Clinical Science Award in 2009 at the International League Against Epilepsy UK Chapter. I have continued working within the field of trial methodology and am an editoral board member for the Cochrane Epilepsy Group.


Research interests

My main interests are: epilepsy therapeutics; psychopharmacology; glioma related epilepsy;music & brain; and functional neurological disorders.

I have current MD/PhD students carrying out the following projects in collaboration with research colleagues in the brain tumour research group and academic psychology

  • Exploring clinical and biological factors in the prognosis and treatment of epilepsy due to high and low grade gliomas (LIMR)
  • Investigating self-perception of emotion in individuals with non-epileptic seizures (NES): using a heartbeat perception task and stroop task test for interoceptive accuracy and executive functioning (LIHS)



  • 1998 BMedSci (Pathology)
  • 2000 MBChB
  • 2004 MRCP (London)
  • 2010 Medical Doctorate (Neurosciences)
  • 2015 FRCP (London)

Professional memberships

  • Royal College of Physicians (London)
  • International League Against Epilepsy UK Chapter

Student education

I have been actively involved in supervising the undergraduate year 3-5 MBChB extended research student projects (ESREP) programme.

Many of my students have found these projects very rewarding and have gained research publications and platform presentations at national and international level. Two ESREP projects under my supervision have been Leng Prize nominated.


Research groups and institutes

  • Leeds Institute of Medical Research at St James's
<h4>Postgraduate research opportunities</h4> <p>We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. Our <a href="https://phd.leeds.ac.uk">research opportunities</a> allow you to search for projects and scholarships.</p>