Professor David Cairns

Profile

I am a Professor of Clinical Trial Research and Director of Late Phase Trials in the Cancer Division at CTRU. I am Deputy Director of the Leeds Cancer Research UK Clinical Trials Unit focussing on large, confirmatory trials in haematological oncology and medical oncology. I joined the CTRU as a Principal Statistician working across the Cancer Division and Comprehensive Health Research Division in July 2013.

I was previously Senior Research Fellow in Biostatistics at the Leeds Institute of Cancer and Pathology where I worked in high-dimensional data analysis related to a number of translational projects in genetics, proteomics, and biomarker discovery and validation. I was the recipient of an MRC Career Development Award in Biostatistics to undertake research in ‘Novel statistical methods for the design and analysis of proteomic experiments for biomarker discovery’.

Responsibilities

• Director of Late Phase Studies in Cancer Division, CTRU
• Deputy Director, Leeds Cancer Research UK Clinical Trials Unit

Research interests

I am interested in the design, conduct and analysis of cancer clinical trials. I work primarily in haematological oncology (multiple myeloma and chronic lymphocytic leukaemia) and some solid tumours (colon, gastro-oesophagael and urological). I am interested in efficient clinical trials that evaluate treatment pathways that are defined by tests such as biomarkers. I am interested in the role of adjunct translational research that brings added value to studies, new challenges in analysis, and helps to design future clinical trials.

Qualifications

• PhD Statistics (University of Sheffield)
• MSc Statistics (University of Sheffield)
• BSc Mathematics (University of Leeds)

Professional memberships

• Fellow of the Royal Statistical Society
• NCRI Multiple Myeloma Subgroup (Member)
• NIHR Clinical Trial Fellowship Panel (Member)
• NIHR Development and Skills Enhancement Fellowship Panel (Member)
• NIHR Doctoral Research Fellowship Panel (Member)
• Cancer Research UK Expert Review Panel (Member)

Research groups and institutes

• Leeds Institute of Clinical Trials Research
• Populations

Projects

<li><a href="//phd.leeds.ac.uk/project/2005-evaluating-the-impact-of-advancements-in-myeloma-treatment-integrating-clinical-trial-and-real-world-data">Evaluating the impact of advancements in myeloma treatment integrating clinical trial and real-world data</a></li> <li><a href="//phd.leeds.ac.uk/project/2004-non-concurrent-control-use-in-confirmatory-platform-trials">Non-concurrent control use in confirmatory platform trials</a></li>