Professor David Cairns
- Position: Professor of Clinical Trials Research
- Areas of expertise: Statistics; Clinical Trials
- Email: D.A.Cairns@leeds.ac.uk
- Phone: +44(0)113 343 1712
- Location: Level 10 Worsley Building
- Website: Twitter | LinkedIn | ORCID
Profile
I am a Professor of Clinical Trial Research and Director of Late Phase Trials in the Cancer Division at CTRU. I am Deputy Director of the Leeds Cancer Research UK Clinical Trials Unit focussing on large, confirmatory trials in haematological oncology and medical oncology. I joined the CTRU as a Principal Statistician working across the Cancer Division and Comprehensive Health Research Division in July 2013.
I was previously Senior Research Fellow in Biostatistics at the Leeds Institute of Cancer and Pathology where I worked in high-dimensional data analysis related to a number of translational projects in genetics, proteomics, and biomarker discovery and validation. I was the recipient of an MRC Career Development Award in Biostatistics to undertake research in ‘Novel statistical methods for the design and analysis of proteomic experiments for biomarker discovery’.
Responsibilities
- Director of Late Phase Studies in Cancer Division, CTRU
- Deputy Director, Leeds Cancer Research UK Clinical Trials Unit
Research interests
I am interested in the design, conduct and analysis of cancer clinical trials. I work primarily in haematological oncology (multiple myeloma and chronic lymphocytic leukaemia) and some solid tumours (colon, gastro-oesophagael and urological). I am interested in efficient clinical trials that evaluate treatment pathways that are defined by tests such as biomarkers. I am interested in the role of adjunct translational research that brings added value to studies, new challenges in analysis, and helps to design future clinical trials.
Qualifications
- PhD Statistics (University of Sheffield)
- MSc Statistics (University of Sheffield)
- BSc Mathematics (University of Leeds)
Professional memberships
- Fellow of the Royal Statistical Society
- NCRI Multiple Myeloma Subgroup (Member)
- NIHR Clinical Trial Fellowship Panel (Member)
- NIHR Development and Skills Enhancement Fellowship Panel (Member)
- NIHR Doctoral Research Fellowship Panel (Member)
- Cancer Research UK Expert Review Panel (Member)
Research groups and institutes
- Leeds Institute of Clinical Trials Research
- Populations
Projects
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<li><a href="//phd.leeds.ac.uk/project/2005-evaluating-the-impact-of-advancements-in-myeloma-treatment-integrating-clinical-trial-and-real-world-data">Evaluating the impact of advancements in myeloma treatment integrating clinical trial and real-world data</a></li>
<li><a href="//phd.leeds.ac.uk/project/2004-non-concurrent-control-use-in-confirmatory-platform-trials">Non-concurrent control use in confirmatory platform trials</a></li>