Dr Marjolaine DEBANT

Dr Marjolaine DEBANT


I studied molecular biology and genetics in Poitiers, France, before completing a PhD in Brest in december 2017. My PhD work focused on perturbations of calcium homeostatsis in an hematological malignancy (chronic lymphocytic leukemia). In March 2018, I moved to Leeds to work with Prof David Beech on the mechanosensitive ion channel Piezo1. My projects aims at understanding better the signalling pathways activated by the channel opening. In 2021, I was awarded with a Mautner-BHF Career Development Fellowship in order to move towards independance, focusing on mechanosensitive pathways and cardiovascular diseases.


Research interests

Mechanosensation in endothelial cells. 

Piezo1 Signalling pathway. Calcium-dependant signalling. 

Cardivascular Diseases. Diabetes. 



  • BSc Molecular and Cellular Biology, and Genetics
  • MSc Molecular and Cellular Biology, and Genetics
  • Ph.D in Immunology

Professional memberships

  • The British Society for Cardiovascular Research

Student education

Tutor for Introduction to Medical Sciences (IMS) module. I supervise undergraduate and postgraduate students. 

Research groups and institutes

  • Leeds Institute of Cardiovascular and Metabolic Medicine
  • Multidisciplinary Cardiovascular Research Centre