Dr Chew Weng Cheng
- Position: Research Fellow
- Areas of expertise: bioinformatics; transcriptomics; genomics; microarray; molecular biology; population genetics
- Email: C.W.Cheng@leeds.ac.uk
- Location: Level 11 Worsley Building
I am a Research Fellow based within the Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM).
I obtained First-class honours in Bachelor of Biomedical Sciences (January 2015) and a PhD in infection and immunity (jointly awarded by the Univesity of Liverpool and Chulalongkorn University in December 2018). During my PhD I have worked extensively on transcriptomics, genomics, peptide microarray, and molecular biology to evaluate a multigene family in Plasmodium vivax as vaccine candidates.
The task now is to apply my knowledge to discover novel therapeutic targets in patients with diabetic heart failure and improve clinical outcome.
Currently, gene expression-based biomarkers have been routinely used in clinical studies to gain a better understanding of disease mechanisms. My main research interest focuses on the discovery of novel biomarkers in large-scale patients with diabetic heart disease. Bulk RNA sequencing and single-cell RNA sequencing are my weapons to (1) scrutinise the entire transcriptome for the discovery of the most promising candidate targets; (2) identification of novel cell types in heterogeneous cell population; and (3) characterising the signatures of gene expression between individual cells.
- BSc Hons
Research groups and institutes
- Leeds Institute of Cardiovascular and Metabolic Medicine