Dr Claudia C Bauer
I am currenty working as as postdoctoral researcher for Dr Robin Bon, where I am working on a British Heart Foundation-funded project investigating small molecule binding sites of TRP channels, using pharmacological and molecular biology techniques.
My previous research has mainly been in the field of vascular biology, with a particular focus on ion channels and the regulation of intracellular calcium. Following an undergraduate degree in Neuroscience, I did a PhD under the supervision of Prof. Chris Peers (University of Leeds), investigating the regulation of endothelial cell calcium by diabetes and gasesous transmitters. I then went on to work as postdoctoral researcher for Dr Alister McNeish (University of Reading), researching the regulation of calcium-actviated K+ channels in the vasculature. Prior to taking up my current position, I worked for Dr Karen Porter (University of Leeds), investigating the effects of diabetes and dietary polyphenols on endothelial cell function.
I am primarily interested in TRPC channels, a family of cation-permeable ion channels that are expressed throughout the body and are thought to be involved in a multitude of (patho)physiologies. In particular, I am interested in how these channels are modulated by small molecules, and I am taking a variety of cell-based approaches to gain further understanding of how these channels function. These include molecular cloning, high-throughput calcium recordings, and photoaffinity labelling using chemical probes.
- PhD University of Leeds (2011)
- BSc (Hons.) Neuroscience (First Class), University of Leeds (2006)
- Early Career Member - British Pharmacological Society
Research groups and institutes
- Leeds Institute of Cardiovascular and Metabolic Medicine