Idris Aurangzeb

• A randomised, phase IIB trial in previously untreated patients with Chronic Lymphocytic Leukaemia (CLL) to compare fludarabine, cyclophosphamide and rituximab (FCR) with FC, mitoxantrone and low dose rituximab (FCM-miniR
• 2. Don’t Smile Co-production theatre and debate – Innovation in research dissemination addressing health literacy and reach to vulnerable at risk young people
• A cluster randomised controlled trial of a structured training programme for caregivers of in-patients after stroke (TRACS)
• A multi-method approach to understanding pain sensitivity pre- and post- non-pharmacological interventions that target alpha wave brain activity
• A randomised controlled trial of an intervention to improve uptake of bowel cancer screening in ethnic and non-ethnic minority groups
• A realist synthesis to explain how, for whom and in what circumstances different community mental health crisis services work. (MH-CREST)
• A review of evidence on skin care for healthy babies at term and to inform the development of practice guidelines
• A study to understand and optimise community hospital care in the NHS (MoCHA)
• A value-based healthcare research ecosystem for adolescents and young adults with cancer
• Acceptability of an online dietary recall tool in women with gestational diabetes
• Acute and chronic effects of 100% Florida Orange Juice consumption on cognitive performance and gut microbiota in 7 - 9 year old UK schoolchildren
• Acute effect of minerals and botanicals (confidential) in combination or isolation on cognitive performance, neural activity, and response to stress
• Adapting and evaluating a complex adaptable intervention to reducing opioid prescribing in primary care (Opioid SMART)
• Addressing depression in Muslim communities
• Addressing what matters to frail older people and their informal carers in primary care based clinical encounters and contacts
• Administration of medicines in care homes (with nursing) for older people by care assistants
• Ageing and working memory
• AKI Diagnostics - The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation
• ALOHA (Effects of almonds on human appetite)
• Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT
• AMIPS
• An electrophysiological investigation of interhemispheric communication in Alzheimer’s Disease.
• An evaluation of the Birth Matters Clinic
• An exploration of the perspectives of chronic pelvic pain amongst women from South Asian backgrounds
• An investigation into the role and regulation of BACE1
• Apps for adolescents with chronic rheumatic disease (CRD): a qualitative study of young people’s, parents’ and professionals’ views on required components of a mobile health-app to support self-care
• ARISE - ARthrItiS and Employment
• Artificial Intelligence based Health, Optimism, Purpose, and Endurance in Palliative Care for Dementia (AI4HOPE)
• Assessing functional ability in older adults
• Assessing functional ability in older adults
• Assessing iodine status and associated health effects in British women during pregnancy
• Assessing research capacity and capability (RECAP) in HCPs: A collaborative pilot study in Leeds Children’s Hospital
• Attune
• Barriers and facilitators to deprescribing for older people living in care homes – PhD study
• Biopassport
• Born in Bradford New Wave
• Breaking the ‘itch-scratch cycle’
• Cancer care co-ordinators and support workers supporting specialist cancer nursing services
• Care Homes Independent Pharmacist Prescribing Study (CHIPPS)
• CHEPSAA
• Children and young people aged 8-15 years with severe allergic eye disease: Development and refinement of a developmentally appropriate Quality of Life measure
• Children and young people with CKD: a qualitative study of their views on desirable components for a developmentally appropriate, CKD-specific information and support software application
• Clinical effectiveness and cost-effectiveness of a multifaceted podiatry intervention for falls prevention in older people
• Clinical trial of a food for special medical purposes (FSMP, confidential) in phenylketonuria
• Cognitive functions and interhemispheric transfer in Alzheimer's
• COMDIS-HSD
• Community dialogues for preventing and controlling antibiotic resistance in Bangladesh
• Community-based complex interventions to sustain independence in older people
• Community-led Responsive and Effective Urban Health Systems (CHORUS)
• COMPARE Establishing components of programmes to reduce restrictive practices: an evidence synthesis
• Constructing Facial Composites: Increasing the Forensic Relevance of Laboratory Research (ESRC)
• CONTRAST Establishing components of interventions to reduce restrictive practices with children and young people: an evidence synthesis.
• CROSS sectional versus invasive imaging in patients with Heart Failure (CROSS-HF)
• Culturally adapted Family Intervention (CaFI) for African Caribbeans with schizophrenia and their families
• Dance On/Dance Activator Programme
• DAPHNE (data-as-a-service platform for healthy lifestyle and preventive medicine)
• Delirium cancer guidelines
• Delivering Digital Drugs
• Developing a novel system of care targeting risk factors for five manifestations of frailty to maintain the independence of older people in hospital and post-discharge (OPTIMISE)
• Developing a service user centred co-designed patient safety intervention for acute mental health wards: A mixed methods process evaluation
• Development and evaluation of strategies to provide longer-term health and social care for stroke survivors and their carers (LoTS-2-Care)
• Development and evaluation of strategies to reduce sedentary behaviour in patients after stroke and improve outcomes (RECREATE)
• Development and testing of strategies to enhance physical activity in care homes (REACH)
• Digital-My Arm Pain Programme (DMAPP) for improving painful distal upper limb musculoskeletal disorders
• DIVERSE (Drivers of eating behaviour during chronic overconsumption)
• Early facilitated discharge in acute mental health
• Effects of a demand-led evidence briefing service on the uptake and use of research evidence by commissioners of health
• Enabling health and maintaining independence for older people at home: the 'HomeHealth'
• Engaging Partners in Childbirth for Prevention of Mother-To-Child Transmission of HIV (EPOCH Study): preliminary work for a randomised controlled trial
• Enhanced in-vivo screening and molecular analysis for colorectal cancer
• ESRC NGO Data Fund
• Ethnicity Training Network
• EU FP7 Collaborative Project
• EVAL-HEALTH
• Evaluating the validity, reliability and acceptability of a seated postural assessment tool for older people with restricted mobility in care homes (The HARP Study)
• Evaluation of national Long COVID data in England
• Evaluation of national Long COVID data in Scotland
• Evaluation of patient preferences for and cost effectiveness of community intravenous antibiotic services (CIVAS)
• Exploring the health benefits of net-zero transport
• EXTEND
• Feasibility study of a supported self-management intervention for stroke survivors with aphasia (StarStep study)
• FIAT (Fistula-in-ano trial) comparing Surgisis® anal fistula plug versus surgeon's preference (advancement flap, fistulotomy, cutting seton)
• Filling without Drilling 
• Finding Ivy: a life worthy of life
• FiTNEss (Myeloma XIV)
• Fostering and sustaining UK, multidisciplinary, family-focused care across the life-course: A White Rose collaboration in long-term condition management
• FReSHSTART: Function Replacement in repeated Self-Harm: Standardising Therapeutic Assessment and the Related Therapy
• Full4Health (Understanding food-gut-brain mechanisms across the lifespan in the regulation of hunger and satiety for health)
• FUsED Study: Frequent users of the Emergency Department: Improving and standardizing services- a mixed methods study
• Gemini Covid-19 study: immediate and longer-term impacts on the health, behaviour and wellbeing of U.K. families
• HALO study: Haematology Lived Experience and Outcomes
• Health Services Research - Development and evaluation of the electronic frailty index+ (eFI+) tool: integrated prognostic-decision modelling to target interventions for older people with moderate or severe frailty
• Healthcare workforce wellbeing, burnout and patient care delivery
• HESVIC
• Home-based Extended Rehabilitation for Older People (HERO)
• How arthritis affects earnings over time
• How low SES men negotiate and construct health practices
• Identifying and managing perinatal mental health in male partners using the Born and Bred in Yorkshire (BaBY) cohort: White Rose collaboration in gender and perinatal mental health
• Impact of an Intervention on Inequalities in Overprescribing - the 3i-o study
• Impact of unrestricted antimicrobial usage on the gut microbiome and antibiotic resistance genes (ARGs) among Bangladeshi population in LMIC context #DhakaGutAMR
• Implementing the six core strategies (6CS) – UK Working in partnership to minimise harm to patients and staff
• Improving outcomes for chronic orofacial pain including temporomandibular disorders – The TMD study
• Improving patient and carer centred outcomes in longer-term stroke care (LoTS Care)
• Improving the safety and continuity of medicines management at care transitions (ISCOMAT) for people with heart failure
• Increasing Physical Activity: Designing and Testing a Workplace Intervention
• Inducing plasticity in the ageing brain
• Innovation to enhance health in care homes: Rapid evidence synthesis
• Intervention study of the effects of phospholipid enriched milk compared with non-enriched milk on cognitive performance and subjective state in 6 - 8 year old UK school children
• Investigating and documenting the school lives of high school pupils living with chronic or life-limiting illness
• Investigating the barriers and facilitators to the prescribing and use of medicines in managing neuropathic pain- PhD study
• Investigation of the Delirium Observation Screening Scale (DOSS) for the routine detection of delirium in the Care Home Setting: The DOSS study
• Leeds Older women Urinary Incontinence Self-Management (LOUISA)
• Let’s talk about the S word: developing an interactive training resource to engage and meet the sexuality and intimacy needs of care home residents.
• Liaison Psychiatry: Measurement and Evaluation of Service Types, Referral Patterns and Outcomes (LP-MAESTRO)
• LOng COvid Multidisciplinary consortium: Optimising Treatments and servIces acrOss the NHS (LOCOMOTION)
• Mainstreaming Global Mental Health
• Marie Curie Industry Academic Partnerships and Pathways
• Medication adherence Validation and feasibility testing of a novel questionnaire to identify barriers to medication adherence
• Methods to estimate health-related quality of life for adults with learning disabilities
• Midland and North of England Stillbirth Study
• MIDSHIPS: Multicentre Intervention Designed for Self-Harm using Interpersonal Problem Solving: A feasibility study
• MindMate 2U – acceptability and feasibility study of a digital resource for young people
• Mole counting pilot for UK Biobank
• Molecular Mechanisms of Vascular Disease
• MUK eight: A randomised phase II trial of Cyclophosphamide and Dexamethasone in combination with Ixazomib, in relapsed or refractory multiple myeloma (RRMM) patients who have relapsed after treatment with thalidomide, lenalidomide and a proteasome inhibit
• Multi-centre Investigation of Cardiac Diffusion Tensor Imaging in Healthy Volunteers by SCMR Cardiac Diffusion Special Interest Group Network (SIGNET)
• My First 1000 Days: A feasibility study of centering-based group care to improve physical, psychological, developmental, and social outcomes of caregivers and infants
• Myeloma XII (ACCoRd)
• Neural correlates of Developmental Coordination Disorder
• Neurodegeneration in the brain
• NICHE-leeds
• NIFTy: Near Infrared Fluorescence (NIRF) Imaging to prevent Post-surgical Hypoparathyroidism (PoSH) after Thyroid Surgery (NIFTy) - A phase II/III pragmatic, multicentre randomised controlled trial
• NoHoW
• Nutrition, growth and health in pre-school children (Growing Well study)
• Oncoscan as a prognostic device to identify high risk of progression to Muscle invasive disease amongst G3T1 Bladder Cancer Patients
• OPTIMAL CARE (Optimising palliative care through electronic coordination).
• Optimising blood pressure management for older people with frailty
• Organising general practice for care homes: A multi-method study
• PARAMEDIC - PreHospital Randomised Assessment of a Mechanical Compression Device in Cardiac Arrest
• Partnerships for Equity and Inclusion
• Partnerships for Social Justice
• Patient Safety Translational Research Centre - Safe Use of Medicines Theme
• PERFORM
• Personalised care planning to improve quality of life for older people with frailty (PROSPER)
• Pharmaceutical Project
• Phase 0 of CBS004 in SSc
• Physical rehabilitation for older people in long-term care
• Prescribing and use of opioids for chronic non-malignant pain: a meta-synthesis of qualitative studies
• Process evaluation embedded within a randomised trial of caregiver training after stroke
• Providing a standardised approach to virtual clinical follow up of total joint replacement
• Providing the foundation for effective decision support for skin problems in primary care
• Raised in Yorkshire (Research Activity in Schools Evaluating Dental Health)
• RCT to compare the bioavailability, acceptability and tolerability and effects on gut microbiota and cognitive function of omega-3 fatty acids in a drink with an equivalent dose of omega-3 fatty acids in capsule form
• Re-imagining professionalism in mental health
• Reducing adolescent smoking initiation
• Relationship between care home staffing and quality of care: a mixed methods approach
• RESPOND
• RESPONSE
• REVAMP
• RISA -IPD ReducIng Self-harm in Adolescents: Individual Patient Data meta-analysis
• RoboHog: developing an in vitro gut model system of the porcine hindgut
• SATIN (SATiety INnovation)
• SINC-Urban
• Smile Aider (Stakeholder Meaningful Involvement Engagement Aiding Dental Research)
• Social networks and infant mortality
• Social Prescribing: A way forward in assisting self-management of osteoarthritis (OA)
• Socially inclusive cities
• SPICES: Seclusion and Psychiatric Intensive Care Evaluation Study
• SPIRITT Scintigraphy for Prediction In Rheumatoid Intentional Therapy Tapering
• STA:RTUPP: Second Time Around: Re-irradiation Treatment Using Photons or Protons.
• Starving livers of glucose for HCC prevention and treatment
• Study to Examine Psychological Processes in Suicidal Ideation and behaviour (STEPPS)
• Supporting young mothers (aged 14-25) in the first two years of life
• Surveys for Urban Equity
• Talking about recovery after stroke: How do we do it, and how can we do better?
• Testing The Health And Therapeutic Potential Of In Vitro Derived Oocytes For The Restoration Of Female Fertility
• The benefits of natural dietary supplements on cognition in ageing
• The Big Picture: Preventing youth substance abuse in Assam
• The CAPTURE study: Cancer Pain-Assessment Toolkit for Use in RoutinE in oncology outpatient services
• The challenges of shared decision making and antipsychotic polypharmacy in forensic settings an interview and observational study
• The Clinical Information and Management System for Stroke (CIMSS)
• The Community Ageing Research Study (CARE 75+)
• The Deep End Leeds
• The detection and management of pain in patients with dementia in acute care settings: development of a decision tool
• The Digital Health Hive
• The Dynamic Assessment of Reading Test (DART) Project
• The effect of ingesting or rinsing sucrose and sucralose solutions on self-control and cognitive performance
• The feeling of what (does not) happen: A multimodal neurobehavioural account of somatosensory misperceptions
• The GEM study: Games for educating midwives in Sub-Saharan Africa
• The Home-based Older People's Exercise Programme (HOPE)
• The Impressed Study
• The INCENTIVE Study: a mixed methods evaluation of an innovation in commissioning and delivery of primary dental care compared to traditional dental contracting.
• The molecular mechanisms of rare genetic disorders.
• The neural integration of emotional expressions from different modalities (University of Leeds Laidlaw Scholarship, 2018)
• The PATCH Study - Package for Residents in Care Homes: a Cluster Randomised Controlled Feasibility Trial
• The RECO study: Realist Evaluation of service models and systems for CO- existing serious mental health and substance use conditions
• The role of circulating epithelial cells (CECs) in autoimmune-mediated fibrotic diseases, such as Scleroderma
• The RP Genome Project: UK Inherited Retinal Dystrophy Consortium
• The safety and quality of the management of medicines when people with dementia move between the care home and hospital setting - PhD study
• Toward blood brain barrier development in assembloids
• Towards modelling an asthma e-health communication tool for young people: a scoping exercise of current practice
• Trans-venous occlusion of incompetent pelvic veins as a treatment for chronic pelvic pain in women: a pilot randomised control trial
• Translation and Application
• Understanding and improving the quality of primary care for prisoners: a mixed methods study (Qual-P)
• Understanding and supporting young adults through the quarter-life crisis
• Understanding how cardiac myosin modulators regulate function in health and disease
• Understanding Japanese "Boys' Love" manga from a UK perspective
• Understanding the Impacts of Care Farms on the Health and Well-being of Probation Service-users: A Pilot study
• Understanding the prevalence, care and management of frailty in care home residents
• Understanding Yaoi/Boys’ Love Chinese Fandom
• Urban Anchal
• Using bespoke IL-23/IL-17A and IL-17F axis gene cards to Gain Clues into Understanding Synovial Mechanisms of Refractory Psoriatic Arthritis
• Using co-production to improve patient carer and staff experiences in health care organizations: a multi-centre, mixed methods evaluation in inpatient stroke units (CREATE)
• Values Based Recruitment: What works for whom, why, and in what circumstances?
• Well on Wheat (WOW) Study
• What does shared decision-making mean to children aged 8-12 years with Acute Lymphoblastic Leukaemia?
• What is the cost-effectiveness of home adaptations for older people?
• Why do stroke patients not receive the recommended amount of therapy? (ReAcT)
• World Health Organisation collaborating centre for nutrition epidemiology

Research groups and institutes

• Leeds Institute of Medical Education

Opportunities

• Diaphragmatic function in malignant hyperthermia
• Epigenetic therapy using ultrasound-triggered microbubble drug delivery for colorectal cancer
• Metabolic regulation of anti-tumour T cell immunity
• 11β-hydroxysteroid dehydrogenase type 1: a novel target to improve wound healing in diabetes
• Atomic force microscopy studies of the molecular mechanisms of nested genes related to tooth formation
• Characterisation of a pre-osteoblast subset of human mesenchymal stem cells: implications for novel osteoarthritis and osteoporosis treatment development
• Combination oncolytic virotherapy for the treatment of Haematological malignancies
• Computational approaches to understanding the mechanosensitive Piezo1 channel activation mechanism
• Developing pluripotent stem cell models of inherited retinal diseases
• Development of a T-cell subset phenotyping, ready-to-use, flow cytometry kit for patients with rheumatoid arthritis
• Digital manufacturing of complete dentures
• Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
• Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
• Exploring the mitotic functions of ASPM in human brain size regulation
• Gastroesophageal reflux in respiratory disease: pathogenic role and improved management
• Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
• Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
• How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
• Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
• IGF axis regulation of matrix mineralisation of dental stem cell populations
• Immunological complicity in evolution of potentially malignant oral lesions
• Improving surgical outcomes for colorectal cancer patients by pre-operative intervention.
• Investigating the genetic association between systemic disease and oral health through genome-wide association study
• Investigation of matrix-mineral interactions of enamel formation in Amelogenesis Imperfecta
• Metabolic labelling approach for the incorporation of functional groups in therapeutic DNA enabling advanced payload delivery strategies in peptide-based gene delivery
• Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
• Novel regulators of +TIP localisation and function
• Oncogenic reprogramming of the immune system
• Oncolytic virus immunotherapy to sensitise liver cancers to immune checkpoint blockade
• Oral health and cognitive function in old age
• Osteochondral tissue engineering using novel epigenetic approaches and multi-layered cell sheet technology
• Partial human genome RNAi screen to identify genes involved in brain size regulation and cancer development.
• Peptide-based matrix gene delivery for tissue regeneration and anti-microbial therapy targeting periodontal disease
• Pre-clinical testing of new therapeutic treatments for cystic kidney disease
• Pre-receptor regulation of glucocorticoid target genes in human skin
• Primary Immunodeficiencies: molecular genetics and the underlying biological mechanisms of disease
• Starving cancer cells to death
• Sun exposure as a novel risk factor for Zika virus infection
• Switching off immunity in health and disease
• The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
• The genetic basis of cognitive impairment in intellectual disability and schizophrenia
• The potential use of bioactive peptides from food and waste as anti-cariogenic agents
• Transient arrest of cell ageing during amplification of human cells in culture
• Understanding the causes of developmental tooth defects using a high-throughput genomic screening approach
• Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
• Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease.