Dr Thuy Do
Dr Thuy Do BSc, MSc, PhD\n\nPrimary research theme: Microbiology and Cell Biology
Thuy Do gained a degree in Biochemistry from the Université Louis Pasteur, Strasbourg, France in 1998. She also holds a BSc (Hons 2ii) in Food Science and Nutrition (1999) and an MSc Analytical Chemistry (2000) from Teesside University, UK and a PhD in Bioprocess Development (2004) from De Montfort University, Leicester.
She held a Postdoctoral Research Associate post at King’s College, London, Department of Microbiology, Dental Institute, Guy’s Hospital, UK from 2004–2012. In 2012 she moved to take a lectureship in Microbiology at the University of Leeds School of Dentistry.
She has experience in planning and conducting research activities, studying oral bacterial diversity and evolution and has engaged in numerous projects which formed part of national and international collaborations. Other important roles have included data handling (statistical analyses, high throughput genome sequence, reads mapping and analyses) as well as writing and publishing results in peer-reviewed journals.\n\nAs a Lecturer in Microbiology, Thuy Do is further developing her research on characterizing the oral microbiome through the use of next generation sequencing technologies. She teaches Microbiology modules to undergraduate dental students and also has supervisory responsibility for undergraduate and postgraduate students.
Oral Biology Research Areas
Thuy Do's research interests include the investigation of the phylogenetic diversity of the oral microbiota and its association with various infectious diseases, as well as the functional biology governing complex interactions within oral biofilms.
Currently, her main focus is the application of high throughput sequencing (HTS) to characterise the oral microbiome, through the use of metagenomics and meta-transcriptomics (RNA-Seq). The aim is to better understand mechanisms of dysbiosis and host-microbiome interactions, with the possibility of enhancing future diagnostic tools. This will be carried out with microbiome profiling and differential gene expression analysis of various biological samples.
Colgate Palmolive (Co-I) 2014-17 Resident oral bacteria with homeostatic potential and their roles in health and disease £107k
Colgate-Palmolive (Co-I) 2018-2020 Oral host microbe homeostasis £350k
Current Postgraduate Research Degree Supervision
Ali Marie, Physico-chemical and mechanical properties of a novel coating for dental implants
Shane McGettrick, Immunomodulation by commensal oral streptococci.
Mona Alshaye (Postgraduate Research Integrated PhD and Master) Responses of the resident oral microbiome of children to amoxicillin therapy.
Teaching Microbiology modules to undergraduate and postgraduate students; supervisory responsibility for undergraduate and postgraduate students.
- Deputy Director of Postgraduate Research Studies