Dr Thomas Baboolal

Dr Thomas Baboolal

Profile

With an undergraduate degree in Biomedical Sciences and a year experience in R&D at a UK based immunodiagnostic company, I continued my studies with a PhD in protein/protein interactions at the lipid membrane at the University of Newcastle with Professor Jeremy Lakey. I then moved to University of Leeds where I was a postdoc with Professor Michelle Peckham and Professor Peter Knight looking at the structure, function and regulation of unconventiaonal myosin motor proteins and actin mutations, which cause cardiomyopathies. In 2010 I moved to the now Leeds Institute of Rheumatic and Musculoskeletal Medicine working with Professor Dennis McGonagle and Dr Elena Jones following up there discovery of a resident population of Mesenchymal Stem Cells within joint synovial fluid.

My research interests are in the therapeutic use and biology of mesenchymal stem cells (MSCs). In particularly the use of minimally manipulated MSCs within the joint to repair soft tissue injuries and cartilage in early osteoarthritis. Through the development of in vitro and in vivo tools to study MSC interactions and behaviours with joint surfaces, biological scaffolds and biological media, we hope to build knowledge and capabilities to utilise the regenerative capacity of these cells. With a focused on understanding the role of MSCs in their native environment and how we can harness these cells it is hoped we can better equip surgeons and physician to met the needs and demands of the patient using their own cells.

Qualifications

  • PG Cert, Professional Innovation Management, Leeds Business School (2014)
  • PhD, Biophysics and Protein Biochemistry, University of Newcastle upon Tyne (2005)
  • BSc (HONS), Biomedical Sciences, Sheffield Hallam University (2001)

Research groups and institutes

  • Leeds Institute of Rheumatic and Musculoskeletal Medicine
  • Regenerative medicine
  • Rehabilitation Medicine
  • Regenerative Medicine Group