Dr Amel Saadi
- Position: Postdoctoral Research Fellow
- Areas of expertise: Role of the stroma in transition from pre-invasive to invasive disease; mammary cell biology; putative cancer stem cells; B cell differentiation; DLBCL
- Email: A.Saadi@leeds.ac.uk
- Phone: +44(0)113 343 8640
- Location: 6.17 Welcome Trust Brenner Building (WTBB)
In September 2000, Amel was awarded an Algerian scholarship to study in the UK. While on a nine months English training course, she gained entry into an undergraduate Masters degree in Biochemistry (MBiochem) at Oxford University. Following graduation in 2005, she went on to complete a PhD in Oncology from Cambridge University in 2010.
Amel was particularly inspired by her experience in the medical research field, starting with the Master’s degree project in epigenetics on a putative enhancer region upstream of the α-globin gene, carried out with Professor Doug Higgs (WIMM, John Radcliffe Hospital, Oxford). During her PhD years, Amel worked with Professor Rebecca Fitzgerald (Cancer Cell Unit, Hutchison MRC Research Centre). Amel’s work investigated the Barrett's metaplasia-dysplasia-adenocarcinoma sequence and tested other upper GI tract lesions to unravel the implication of the microenvironment, namely the stroma, in inflammatory pathways and the transition from pre-invasive to invasive disease.
Amel then embarked on a 4-year research fellowship in cellular biology. She worked with Dr John Stingl on the controversial topic of breast cancer stem cells (Mammary group, CI, Cancer Research-UK). She learnt many in vitro and in vivo models for the study of adult stem cells. During her postdoctoral experience, she also taught pathology to “Natural Sciences Tripos part I” students (Girton College, Cambridge University).
In May 2015, Amel joined the Molecular Haematology Research Group as a postdoctoral research fellow, working with Professor Reuben Tooze and Dr Gina Doody at the Leeds Institute of Medical Research (LIMR). Amel currently works on the interesting and potentially important role of the transcription factor ZBTB32 in both B cell physiology (differentiation) and pathology (namely, ABC-DLBCL).
- PhD in Oncology
- April 2011- January 2014: Associate Faculty member of F1000 post-publication peer review international faculty
Amel contributes to the delivery of Mechanisms of disease pathology module to undergraduate nd year medical students (MBchB). She is also to be involved in reviewing long essays submitted for the taught postgraduate module Cancer Biology & Molecular Oncology.2
Research groups and institutes
- Leeds Institute of Medical Research at St James's