I have an undergraduate degree in biomedical chemistry and a PhD in regenerative medicine which focussed on the understanding of mesenchymal stem cell biology and their application to cell based therapy.
Form there I moved on to investigating stem cell immune cell interactions in the context of inflammatory arthritis particularly spondyloarthritis. I have collaborated extensively with industry including Novartis, Miltenyi Biotec and Pfizer.
I am involved in teaching part of the undergraduate Medicine syllabus and currently act as the lead supervisor for 2 postgraduate students.
Richard J Cuthbert, Evangelos M. Fragkakis, Robert Dunsmuir, Zhi Li, Mark Coles, Helena Marzo-Ortega, Peter Giannoudis, Elena Jones, Yasser El-Sherbiny, Dennis McGonagle.
Group 3 Innate Lymphoid Cells in Human Enthesis. Arthritis and Rheumatology. 2017 May 16.
R. Cuthbert, P. Giannoudis, X.Wang, L. Nicholson, D. Pawson, A. Lubenko, H.B. Tan, A. Dickinson, D. McGonagle, E. Jones.
Examining the feasibility of clinical grade CD271+ enrichment of mesenchymal stromal cells for bone regeneration. PLoS One. 2015. In Press
Cuthbert RJ, Churchman SM, Tan HB, McGonagle D, Jones E, Giannoudis PV Induced periosteum a complex cellular scaffold for the treatment of large bone defects.
.Bone. 2013 Dec;57(2):484-92. doi: 10.1016/j.bone.2013.08.009. Epub 2013 Aug 15.
Cuthbert R, Boxall SA, Tan HB, Giannoudis PV, McGonagle D, Jones E.
Single-platform quality control assay to quantify multipotential stromal cells in bone marrow aspirates prior to bulk manufacture or direct therapeutic use.
Cytotherapy. 2012 Apr;14(4):431-40. doi: 10.3109/14653249.2011.651533. Epub 2012 Jan 24.
Cuthbert RJ, Wilson JM, Scott N, Coletta PL, Hull MA.
Differential CD74 (major histocompatibility complex Class II invariant chain) expression in mouse and human intestinal adenomas.
Eur J Cancer. 2009 Jun;45(9):1654-63. doi: 10.1016/j.ejca.2009.02.005. Epub 2009 Mar 9.
- BSc Biomedical chemistry
- Phd Regenerative medicine
Undergraduate tutor - Undergraduate Medicine
Lead PhD supervisor - Postgraduate research
Research groups and institutes
- Leeds Institute of Rheumatic and Musculoskeletal Medicine
- Regenerative Medicine Group